For nearly three decades, The Children’s Heart Foundation has been the nation's leader in the field of congenital heart defect research…and it’s all thanks to you.

We're proud to be launching our "Funding Research from the Heart" campaign to raise more funds for life-changing research. This campaign is more than just a fundraiser; it's a crucial part of our mission to support the most promising research into congenital heart defects. From now until the end of the year, our annual giving campaign offers you a unique opportunity to join us in this vital effort and make a significant impact.

The revolutionary breakthroughs of tomorrow depend on what you do today. Will you be a “Heart Champion” and help fund this essential research? Your generosity and commitment to our cause are invaluable.

By supporting The Children's Heart Foundation, you become an integral part of a larger purpose that brings hope and healing to children and families impacted by congenital heart defects. Thank you for being part of this important mission.

Your Support In Action: 2023 Research Funding Highlights

  • The aim of this research is to carry out proof-of-concept feasibility studies for an implantable Fontan pump that is internally powered and does not require external energy. The findings will set the stage for NIH funding to carry out preclinical hemocompatibility development. The technology will have long-term impact on quality of life and lifespan of patients with single functional ventricle.

    This research was funded in part by The Haley Foundation through their generous matching gift made to CHF's "Matching from the Heart" Campaign.

  • The pulmonary veins are a collection of vessels delivering oxygen-rich blood from the lungs to the heart. Narrowing of a pulmonary vein, known as pulmonary vein stenosis (PVS), is a serious and progressively life-threatening disease. The collective results of this study will provide foundational data to secure funding for a larger clinical study that improves long-term outcomes in PVS patients treated by stenting.

  • Children born with single ventricle congenital heart disease undergo a series of operations, including the Fontan procedure, to restore adequate heart function and allow normal growth. A new form of chronic liver disease, which has been named ‘Fontan-associated liver disease’ (FALD), has been observed in patients with Fontan physiology, and it has become evident that nearly all patients have evidence of FALD on liver biopsy by young adulthood. The long-term goal of this project is to develop reliable non-invasive testing strategies that accurately reflect histological severity of FALD to guide transplant teams regarding combined-heart liver transplantation (CHLT) candidacy.

    This project was funded in part by the Cortney Gives BAK Foundation.

  • In this study, researchers will develop and characterize human pluripotent stem cell-derived cardiac pacemakers. Outcomes of the proposed project will define a human stem cell technology-driven cell product toward innovation in cardiac pacing.