Informing developmental screening and evaluation procedures for young infants with complex congenital heart defects

Doctor's Name: 
Heathcock, Jill, MPT, PhD
Hospital/Institution: 
The Ohio State University

Collaboratively awarded through the CHF and AHA Congenital Heart Defect Research Awards

 (Total Grant Amount $140,000; CHF portion = $74,160)

Children with single ventricle congenital heart lesions account for 25-40% of all neonatal cardiac deaths. Between 35-50% of these kids will experience an unanticipated acute cardio-respiratory arrest event within the first 3 months of life, and 15% will expire over this same time period. This study addresses the current inability to accurately detect the onset of acute cardio-respiratory arrest events in this population. We intend to validate a system which provides a 1-2 hour early warning notice to care team members of an imminent arrest, which would allow them to proactively respond to mitigate arrest events before they become life threatening, decreasing mortality and morbidity of these children.

This study directly impacts the mission of the AHA by creating a new clinical diagnostic tool which can be used to help prevent life-threatening cardio-respiratory arrest events in children with congenital heart defects. The predictive algorithm described in this study represents a fundamental shift in the way that these critically ill patients are monitored: a shift from reactive care to proactive care. We know that the sooner an intervention can be applied, the larger its protective effect. This translates into decreased length of stay, lower mortality and morbidity, as well as reduced cost of care for these children. The technologies and methodologies developed by this study are immediately applicable to other cardiac populations, both in the pediatric as well as adult populations.

 

Award Date 1: 
2016
Award Amount 1: 
$74,160